• Collaborate and save on travel
  • Free for 30 Days
  • Designed specifically for education in K-12, professional, corporate, and government organizations worldwide.
  • Wide spectrum of collaboration- Web, Video, and Audio Conferencing, Presence and Instant Messaging, Voice Authoring and Collaboration
  • Perfect for LMSs, because it facilitates a 21st Century learning and teaching environment.
  • Interactive Whiteboard
  • 6 languages

  • Collaborate and save on travel
  • Free basic face-to-face video conferencing, instant messaging, and screen sharing
  • Designed for a more personal video conferencing experience and on mobile phones, but also professional use such as Skype for Classroom, and Business
  • Skype in the Classroom is a free global community
  • Video Conferencing in HD
  • Group conferencing for paid premium members
  • 32 languages

One of the major differences is that Skype is free and Blackboard Collaborate is not. Another large difference is that Blackboard Collaborate is designed for education in mind and may be used by professional organizations. Skype is designed to be user friendly for everyone from young to old. Skype is also available on devices such as Mobile phones. I found Skype to have many more language exchanges.
Both of them claim to cut costs on travel to meetings and offer group or collaborate meeting areas where sharing files, instant messaging, and face-to-face web conferencing are available. Both of them claim to provide a safe and secure network to use for video conferencing.